Periportal fibrosis in Schistosoma mansoni Mono and Malaria- Schistosoma Co-infected Individuals in Finchaa Sugar Estate, Western Ethiopia
DOI:
https://doi.org/10.20372/mhsr.v1i1.7Keywords:
Co-infections, Co-morbidity, Periportal fibrosis, Plasmodium falciparum, Plasmodium vivax, Finchaa Sugar EstateAbstract
In Ethiopia where malaria parasite and Schistosoma mansoni infections are co-endemic, the general population is quite vulnerable both to malaria and Schistosoma mansoni infections singly or concomitantly. However, data on PPF due to single and co-infections are lacking. The aim of this study was to assess the status of PPF in S. mansoni mono infected and malaria-S. mansoni co-infected individuals. A community based cross sectional study was conducted in Finchaa Sugar Estate, western Ethiopia. Schistosomal periportal and portal liver fibrosis were determined by ultrsonography. SPSS statistical software version 20 was used and P-value <0.05 was reported as statistically significant. The findings of this study showed that P. falciparum and S. mansoni co-infection reciprocally increase the degree of PPF. The study has provided an additional sonographic data on the reciprocal effects of P. falciparum and S. mansoni co-infection, and could serve as a guide in designing, developing and implementing intervention strategies to mitigate co-morbidity due to co-infection among the high risk groups in Ethiopia and other endemic areas of the world.
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