Phytochemical Screening and Characterization of Olean-18-ene Type Triterpeniod from the Roots of Lantana camara
Keywords:
Lantana camara, Terpene, Olean-18-ene type triterpeneAbstract
Lantana camara, commonly called wild or red sage or sleeper weed is the most widely spread species of the genus Lantana traditionally used to treat various diseases such as diarrhea, fever, and stomachache. It has also been reported to show antifungal, antiproliferative, insecticidal, antimicrobial and germicidal activity. Phytochemical screening of the methanol extract revealed the presence of flavanoids, terpenes, saponins and the absence of anthraquinones and alkaloids. Silica gel column chromatographic separation of the methanol root extract yielded an olean-18-ene type triterpene. Complete characterization of the isolated compound was done using spectroscopic techniques (UV-Vis, IR, 1H-NMR, 13C- NMR, DEPT-135, COSY, HMBC and HSQC).
Downloads
Metrics
References
Chiang, L.C., Chiang W., Chang M.Y., Ng L.T., Lin C.C. (2003). Antileukemic activity of selected natural products in Taiwan. American Journal of Chinese Medicine 31(1):37-46
Debjyoti, D. (1995). Biochemistry 8th Ed., Academic publishers, Kolkata, p 39.
Farnsworth, N.R. (1996). Phytochemical screening of the biologically active compounds from higher plants. Journal Pharmaceutical Sciences 55:227-276.
Ganjewala, D., and Dipita, B. (2009). Effect of leaf positions on total phenolics, flavonoids and proantho-cyanidins content and Antioxidant Activities in Lantana camara. Journal of Scientific Research 2:363-369.
Ghisalberti, E.L. (2000). Lantana camara (Verbenceae).
Fitoterapia 71: 467-486.
Hua, S., Wei-Shuo, F., Wen-Zhao, W., Chun, H., (2006). Structure-activity relationships of oleanane- and ursane- type triterpenoids. Botanical Studies 47: 339-368.
Johns, S.R., Lamberton, J.A., Morton, T.C., Suares, H., Willing, R.I. (1983a). Triterpenes of Lantana tiliaefolia. 24- Hydroxy-3-oxours-12-en-28-oic acid, a new triterpene. Australian Journal of Chemistry 36: 2537-2547.
Johns, S.R., Lamberton, J.A., Morton, T.C., Suares, H., Willing, R.I. (1983b). 22β-[(S)-2-Methylbutanoyloxy]-3- oxoolean-12-en-28-oic acid, a new constituent of Lantana camara. Australian Journal of Chemistry 36: 1895-1902.
Leak, S.G.A. (1999).Tsetse biology and ecology, their role in the epidemiology and control of trypanosomosis. CAB International, Wallingford, UK.
Mesfin, F., Demissew, S., Teklehaymanot, T. (2009). An ethnobotanical study of medicinal plants in Wonago Woreda. Journal of Ethnobiology and Ethnomedicine 5(28):1-18.
Nayak, B.S., Raju, S.S., and Ramsubhag, A. (2008). Investigation of wound healing activity of Lantana camara in Sprague dewily rats using a burn wound model. International Journal of Applied Research in Natural Products 1: 15-19.
Nagao, T., Abe, F., Kinjo, J. (2002). Antiproliferative constituents in plants: Flavones from the leaves of Lantana montevidensis Briq. and consideration of structural relationship. Biochemical Pharmaceutical Bulletin 25: 875-879.
Rajakaruna, N., Harris, C.S., Towers, G.H.N. (2002). Antimicrobial activity of plants collected from serpentine outcrops in Sri Lanka. Pharmaceutical Biology 40:235- 244.
Rios, M.Y., Salinas, D., Villarreal, M.L. (2001). Cytotoxic Activity of Moronic Acid and Identification of the New Triterpene 3,4-seco-Olean-18-ene-3,28-dioic Acid from Phoradendron reichenbachianum, Planta Medica 67: 443-
Ross, I.A. (1999). Medicinal plants of the world: Chemical composition, traditional and modern medical uses. Totowa, New Jersey Human Press 2: 487-490.
Sankaran, K.V. (2007). Lantana camara. Invasive Species Fact Sheet. Asia-Pacific Forest Invasive Species Network, Food and Agricultural Organization of the United Nations (FAO).
Singh, S.K, Trpphathi, V.J., Singh, R.H. (1991). A new pentacyclic triterpene acid from Lantana indica. Journal of Natural Products 54(3):755-758.
Singh, S.K, Triphathi, V.J., and Singh, R.H. (1990). 3β, 24- Dihydroxyolean-12-en-28-oic acid, apentacyclic triterpene acid from Lantana indica. Phytochemistry 29(10):3360- 3362.
Sofowora, A. (1982). Historical review of traditional medicine. In, medicinal plants and traditional medicine in Africa. John wily and Sons Ltd., Chichester, USA, 9-12.
Tripathi, A.K., Shukla, B.N. (2002). Antifungal activity of some plant extracts against Fusarium oxysporum sp. causing wilt of linseed. Journal of Mycology and Plant Pathology 32: 266-267.
Downloads
Additional Files
Published
How to Cite
License
Copyright (c) 2015 journal of Science, Technology and Arts Research
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
STAR © 2023 Copyright; All rights reserved