In vitro Anthelmintic Activity of Different Extracts of Memecylon umbellatum Burm.
Keywords:
Memecylon umbellatum, Pheretima PosthumaAbstract
In the present study, the possible anthelminitic effects of different extracts (petroleum ether, chloroform, and ethanol) and two isolated compounds β-stigmasterol β (PI) and Sitosterol (PII) from the leaves of Memecylon umbellatum on Indian earthworms Pheretima Posthuma was investigated by in vitro experiments. Various concentrations (25, 50, 100mg/ml) of all extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. From the activity results it was found that, that the ethanolic extract and pure compound PI having the equipotent activity with standard drug albendazole. Form the observations made higher concentration of extract produced paralytic effect much earlier and the time to death was shorter for all worms.
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