Anticariogenic Activity of Lagerstroemia speciosa (L.)

Authors

  • Vivek M.N SRNMN College of Applied Sciences
  • Pramod N.J SRNMN College of Applied Sciences
  • Prashith Kekuda T.R SRNMN College of Applied Sciences
  • Mukunda S SRNMN College of Applied Sciences
  • Mallikarjun N Sahyadri Science College

Keywords:

Lagerstroemia speciosa, Anticariogenic, activity Streptococcus, mutans, Agar well diffusion

Abstract

Dental caries is the common infectious diseases of the oral cavity and is caused mainly by oral streptococci. The present study was carried out to investigate the anticariogenic activity of methanol extract of Lagerstroemia speciosa (L.) (Lythraceae) leaves. The inhibitory efficacy of methanol extract was tested against 12 oral isolates of Streptococcus mutans by Agar well diffusion method. The broth cultures of bacteria were swabbed uniformly on sterile Brain heart infusion agar plates and wells of 6mm were punched in the inoculated plates. Standard antibiotic and different concentrations of extract were transferred into labeled wells. Zone of inhibition was measured after incubation. The extract caused a concentration dependent inhibition of cariogenic isolates. Inhibition caused by standard antibiotic was higher than the methanol extract. Preliminary phytochemical analysis showed the presence of saponins, glycosides, tannins and terpenoids. The result of the present study reveals that methanol extract showed significant inhibitory activity against cariogenic isolates. The inhibitory efficacy of extract against cariogenic isolates could be due to the presence of these metabolites. In suitable form, the leaves could be used to treat dental caries.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

Vivek M.N , SRNMN College of Applied Sciences

Department of Microbiology, SRNMN College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India.

Pramod N.J, SRNMN College of Applied Sciences

Department of Microbiology, SRNMN College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India.

Prashith Kekuda T.R, SRNMN College of Applied Sciences

Department of Microbiology, SRNMN College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India.

Mukunda S, SRNMN College of Applied Sciences

Department of Microbiology, SRNMN College of Applied Sciences, NES Campus, Balraj Urs Road, Shivamogga-577201, Karnataka, India.

Mallikarjun N, Sahyadri Science College

Department of Studies and Research in Microbiology, Sahyadri Science College (Autonomous), Shivamogga-577203, Karnataka, India.

References

Chung, J.Y., Choo, J.H., Lee, M.H. and Hwang, J.K. (2006). Anticariogenic activity of macelignan isolated from Myristica fragrans (nutmeg) against Streptococcus mutans. Phytomedicine 13(4): 261-

Esmaeelian, B., Kamrani, Y.Y., Amoozegar, M.A., Rahmani, S., Rahimi, M. and Amanlou, M. (2007). Anti-cariogenic properties of malvidin-3,5- diglucoside isolated from Alcea longipedicellata against oral bacteria. International Journal of Pharmacology 3: 468-474.

George, N.J., Obot, J.B., Ikot, A.N., Akpan, A.E. and Obi-Egbedi NO. Phytochemical and Antimicrobial properties of leaves of Alchonea cordifolia. E- Journal of Chemistry 27(3): 1071-1079.

Kekuda, T.R.P., Raghavendra, H.L., Swathi, D., Venugopal, T.M., Vinayaka, K.S.. Antifungal and Cytotoxic Activity of Everniastrum cirrhatum (Fr.) Hale. Chiang Mai Journal of Science 39(1): 76-83.

Khare, C.P. (2007). Indian Medicinal Plants- An illustrated dictionary. Springer-Verlag, Berlin/ Heidelberg. Pp 358-359.

Lim, S.H., Seo, J.S., Yoon, Y.J., Kim, K.W., Yoo,

S.Y., Kim, H.S., Kook, J.K., Lee, B.R., Cha, J.H

and Park, J.Y. (2003). Effect of leaf-extract from Camellia sinensis and seed-extract from Casia tora on viability of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces. Korean Journal of Orthodontics 33: 381- 389.

Loesche, W.J. (1986).The identification of bacteria associated with periodontal disease and dental caries by enzymatic methods. Oral Microbiology and Immunology 1: 65-70.

Song, J.H., Yang, T.C., Chang, K.W., Han, S.K., Yi,

H.K. and Jeon, J.G. (2006). In vitro anti-cariogenic activity of dichloromethane fraction from Rheum undulatum L. root. Archives in Pharmcological Research 29(6): 490-496.

Swathi, D., Suchitha, Y., Venugopal, T.M., Kekuda, P.T.R., Mallikarjun, N. (2011). Inhibitory Efficacy of Croton gibsonianus Nimm. Grah (Euphorbiaceae) Against Oral Isolates of Streptococcus mutans. International Journal of Pharmaceutical & Biological Archives 2(3): 896-899.

Thurnheer, T., Gmur, R., Giertsen, E. and Guggenheim, B. (2001). Automated fluorescent in situ hybridization for the specific detection and quantification of oral streptococci in dental plaque. Journal of Microbiological Methods 44: 39-47.

Venugopal, T.M., Swathi, D., Suchitha, Y., Kekuda, T.R.P., Mallikarjun, N., Soundarya, S., Eyasu, E., Raghavendra, H.L. (2011). Mineral Composition, Cytotoxic and Anticariogenic Activity of Scleropyrum pentandrum (Dennst.) Mabb. International Journal of Drug Development & Research 3(4): 344-350.

Whiley, R.A. and Beighton, D. (1998). Current classification of the oral streptococci. Oral Microbiology & Immunology 13: 195-216.

Yanagida, A., Kanda, T., Tanabe, M., Matsudaira, F. and Cordeiro, J.G.O. (2000). Inhibitory effects of Apple Polyphenols and Related Compounds on Cariogenic Factors of Mutans Streptococci. Journal of Agricultural & Food Chemistry 48(11): 5666- 5671,

Zheng, C.J., Oh, H.W. and Kim, W.G. (2010). Potent anticariogenic activity of Aceriphyllum rossii and its components, aceriphyllic acid A and 3-oxoolean-12

-en-27-oic acid. Journal of Food Science 75(2): 78- 82.

Downloads

Published

30.03.2012

How to Cite

M.N , V., N.J, P., Kekuda T.R, P., S, M., & N, M. (2012). Anticariogenic Activity of Lagerstroemia speciosa (L.). Journal of Science, Technology and Arts Research, 1(1), 53–56. Retrieved from https://journals.wgu.edu.et/index.php/star/article/view/18

Issue

Section

Short Communication

Categories

Plaudit

Most read articles by the same author(s)

1 2 > >>